Unable to eradicate Open Software Updater

I have a Windows 10 PC that I have been unable to completely eradicate "Open Software Updater" adware banners. The PC has MalwareBytes Premium installed. The adware banners manifest themselves when playing Words with Friends in Facebook. It happens in both Internet Explorer and Edge on no particular schedule.
Here is what I have tried so far.
Uninstalled "Open Software Updater" using Control Panel
Malwarebytes Support Tool
FRST scan
ADWCleaner
Hitman Pro
CCCleaner
Deleted history, checked...

Unable to eradicate Open Software Updater